Concomitant Multidrug-resistant Pulmonary Tuberculosis and Susceptible Tuberculous Meningitis

نویسندگان

  • Christine Bernard
  • Florence Brossier
  • Mathilde Fréchet-Jachym
  • Philippe C. Morand
  • Sophie Coignard
  • Elisabeth Aslangul
  • Alexandra Aubry
  • Vincent Jarlier
  • Wladimir Sougakoff
  • Nicolas Veziris
چکیده

506 Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 20, No. 3, March 2014 medical interest in the region of eastern Senegal [in French]. Bull Soc Pathol Exot. 1993;86:21–8. 5. Niklasson B, Peters CJ, Grandien M, Wood O. Detection of human immunoglobulins G and M antibodies to Rift Valley fever virus by enzyme-linked immunosorbent assay. J Clin Microbiol. 1984;19:225–9. 6. Cornet M, Robin Y, Chateau R, Hème G, Adam C. Isolation of arboviruses in east Senegal from mosquitoes (1972–1977) and notes on the epidemiology of viruses transmitted by Aedes, especially of yellow fever virus. Cah ORSTOM Sér Ent Méd. et Parasitol. 1979;17:149–63.

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Background Drug-resistant tuberculous meningitis (TBM) is difficult to diagnose and treat. Mortality is high and optimal treatment is unknown. We compared clinical outcomes of drug-resistant and -susceptible TBM treated with either standard or intensified antituberculosis treatment. Methods We analyzed the influence of Mycobacterium tuberculosis drug resistance on the outcomes of patients wit...

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Multidrug-resistant (MDR) pulmonary tuberculosis (TB) is well described in the literature. Reports of MDR TB meningitis (MDR-TBM), however, are limited to case reports and a single case series. During the period of 1999-2002, 350 patients with TBM were identified by cerebrospinal fluid culture for TB. Thirty patients (8.6%) had TB that was resistant to at least isoniazid and rifampicin. All 30 ...

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عنوان ژورنال:

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2014